The Book of Sin - Defeat all 7 Deadly Sin mini-bosses

With a bit of luck and perseverance you will eventually get all four Balls of Bandages to create Super Bandage Girl. If this happens, you must restart as Conquest will only ever drop the White Pony item. The last obstacle comes with Womb I which has a chance to spawn the Harbinger called Conquest instead of Death. Unfortunately, even this strategy is not fool proof as double trouble boss rooms cannot be changed and you cannot force the fight instead of Mom or Mom's Heart. Always use it on the first floor of a chapter to be safe. If they drop Cube of Meat, restart and try again. The Harbingers are necessary as they always drop either Cube of Meat or Ball of Bandages. Whenever you use the Book of Revelations, it forces one of the bosses for the current chapter to be one of the four Harbinger bosses. The easiest way to do this is to restart your run until you get the Book of Revelation in either the Item Room or a Library.

Balls of Bandages can only be found by defeating a Harbinger boss (Famine, Pestilence, War and Death). Something Sticky - Beat Chapter 3 20 timesĪ Bandage - Make a Super Bandage Girl by collecting 4 Balls of Bandages. Something from the Future - Beat The Basement 40 times

Loki's Horns - Defeat Lokii for the first time Lil' Chubby - Beat Chapter 2 for the first time Monstro's Tooth - Beat Chapter 1 for the first time The Harbingers - Defeat Mom for the first timeĪ Cube of Meat - Defeat Mom for the first timeīook of Revelations - Defeat a Harbinger for the first timeĪ Fetus in a Jar - Defeat Mom's Heart 9 times Magdalene - Have 7 or more red heart containers at once I won't go into great detail unless it is necessary and not explained elsewhere. A lot of these will likely be repeated on other pages as they are also tied to some achievements. As of Afterbirth+ there are 178 and all are needed for PG, RPG and 1001%.

Secrets are essentially in-game achievements. Ending 16 - Unlocked by defeating Mega Satan for the first time.Įnding 17 (Afterbirth) - Unlocked by defeating Hush for the first time.Įnding 18 (Afterbirth) - Unlocked by defeating Ultra Greed in Greed Mode for the first time.Įnding 19 (Afterbirth+) - Unlocked by defeating Ultra Greed in Greedier Mode for the first time.įinal Ending (Afterbirth+) - Unlocked by defeating Delirium for the first time.

Binding of isaac rebirth strategy